“Therefore the wrath of the Lord was kindled against His people, so that He abhorred His own inheritance. And He gave them into the hand of the Gentiles, and those who hated them ruled over them. Their enemies also oppressed them, and they were brought into subjection under their hand. Many times He delivered them; But they rebelled in their counsel, and were brought low for their iniquity.” – Psa. 106:40-43
There are real consequences for defying God.